Many diseases of the nervous system are difficult to treat but can be prevented when we have adequate genetic information. This work covers the genetics of neurological disorders. It conveys practical clinical advice to neurologists, geneticists and paediatricians, emphasising diagnosis, mode of inheritance and recurrence risks.
BACK COVER COPY This third edition of The Genetics of Neurological Disorders incorporates the recent advances in genetics and molecular genetics into this comprehensive classic work. The classification of diseases within the text has been updated in line with the change in practice necessitated by these recent advances. Invaluable for both the geneticist and the neurologist, this book provides up-to-date information about counselling recurrence risks across the wide range of conditions seen by both the adult and paediatric neurologist. Each condition is covered in a way that helps the clinician reach a diagnosis before counselling, and carrier detection and prenatal diagnosis are also discussed for many conditions. Reviews of previous editions: ''...coherent, well organised, extremely well-documented work....This is a fine book to take to the clinic as well as the library'' New England Journal of Medicine ''No neurologist will care to function from now on without ready access to this book, and it will be consulted by all clinical geneticists.'' Annals of Human Genetics ''The strength of this book lies in the scholarly treatment of both old and new literature pertaining to familial neurological diseases. This book can heartily be recommended to the clinician seeking information on the genetics of neurological disease.'' Brain ''As a comprehensive source of reference it is unrivalled... a unique compilation of great importance which sets out all the current information about genetic elements, markers and calculations of risk. No neurologist can afford to be without a copy close to hand.'' Journal of Neurology, Neurosurgery and Psychiatry NOT on Back cover - Additional reviews ''This edition has grown by 257 worthwhile pages'' British Medical Journal on 2e ''The book is very successful indeed, combining a rigorous academic analysis of evidence for any genetic statement with clear English.'' Archives of Disease in Childhood on 1e ''...encyclopaedic coverage of the literature, ranging from major studies of larger populations to single families exhibiting obscure conditions...'' Journal of Nervous and Mental Diseases on 1e ''The book is a comprehensive compendium which presents the facts clearly'' Developmental Medicine and Child Neurology on 1e ''...the best of its kind...with wonderfully succinct summaries and replete with over 200pp of references... outstanding value...it will deservedly find itself very widely used and referred to with pleasure, providing as it does so lucid and informative a guide to a complex and painful subject matter.'' Genetic Research, Cambridge on 2e
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