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Mutation, Randomness, and Evolution

By: (Author) Dr Arlin Stoltzfus

Extended Catalogue

Ksh 17,900.00

Format: Hardback or Cased Book

ISBN-10: 019884445X

ISBN-13: 9780198844457

Publisher: Oxford University Press

Imprint: Oxford University Press

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Apr 22nd, 2021

Print length: 288 Pages

Weight: 788 grams

Dimensions (height x width x thickness): 19.60 x 25.40 x 1.90 cms

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The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection.
What does it mean to say that mutation is random? How does mutation influence evolution? Are mutations merely the raw material for selection to shape adaptations? The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection. The successes of this research program created a blind spot - in mathematical models and verbal theories of causation - that has stymied efforts to re-think the role of variation. However, recent theoretical and empirical work shows that mutational biases can and do influence the course of evolution, including adaptive evolution, through a first come, first served mechanism.This thought-provoking book cuts through the conceptual tangle at the intersection of mutation, randomness, and evolution, offering a fresh, far-reaching, and testable view of the role of variation as a dispositional evolutionary factor. The arguments will be accessible to philosophers and historians with a serious interest in evolution, as well as to researchers and advanced students of evolution focused on molecules, microbes, evo-devo, and population genetics.

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