During the early years of the AIDS epidemic, thousands of Americans became infected with HIV through the nation's blood supply. Because little reliable information existed at the time AIDS first began showing up in hemophiliacs and in others who had received transfusions, experts disagreed about whether blood and blood products could transmit the disease. During this period of great uncertainty, decision-making regarding the blood supply became increasingly difficult and fraught with risk. This volume provides a balanced inquiry into the blood safety controversy, which involves private sexual practices, personal tragedy for the victims of HIV/AIDS, and public confidence in America's blood services system. The book focuses on critical decisions as information about the danger to the blood supply emerged. The committee draws conclusions about what was done—and recommends what should be done to produce better outcomes in the face of future threats to blood safety. The committee frames its analysis around four critical area:Product treatment—Could effective methods for inactivating HIV in blood have been introduced sooner?Donor screening and referral—including a review of screening to exlude high-risk individuals. Regulations and recall of contaminated blood—analyzing decisions by federal agencies and the private sector. Risk communication—examining whether infections could have been averted by better communication of the risks. Table of ContentsFront MatterExecutive Summary1 Introduction2 The U.S. Blood Supply System3 History of the Controversy4 Product Treatment5 Donor Screening and Deferral6 Regulations and Recall7 Risk Communication to Physicians and Patients8 Conclusions and RecommendationsAppendixesA Individuals Interviewed by the CommitteeB Individuals Providing Oral and Written TestimonyC Chronological Summary of Critical Events, NHF Communications, Knowledge Base, Risk Assessment, Clinical Options, and NHF ActionsD Key Documents Provided to the CommitteeE Glossary of Acronyms and TermsF Committee and Staff BiographiesIndex
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